| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMD1 | DNMT1 | ENSAPLP00000014743 | ENSAPLP00000002034 | S-adenosylmethionine decarboxylase proenzyme. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.905 |
| AMD1 | GNMT | ENSAPLP00000014743 | ENSAPLP00000025948 | S-adenosylmethionine decarboxylase proenzyme. | Glycine N-methyltransferase. | 0.961 |
| AMD1 | MAT1A | ENSAPLP00000014743 | ENSAPLP00000019358 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.943 |
| AMD1 | MAT2A | ENSAPLP00000014743 | ENSAPLP00000031713 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.943 |
| AMD1 | MAT2B | ENSAPLP00000014743 | ENSAPLP00000029552 | S-adenosylmethionine decarboxylase proenzyme. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.919 |
| AMD1 | MTR | ENSAPLP00000014743 | ENSAPLP00000009750 | S-adenosylmethionine decarboxylase proenzyme. | 5-methyltetrahydrofolate-homocysteine methyltransferase. | 0.478 |
| AMD1 | TAT | ENSAPLP00000014743 | ENSAPLP00000027353 | S-adenosylmethionine decarboxylase proenzyme. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.558 |
| AMD1 | U3IS18_ANAPP | ENSAPLP00000014743 | ENSAPLP00000010041 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.943 |
| DNMT1 | AMD1 | ENSAPLP00000002034 | ENSAPLP00000014743 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme. | 0.905 |
| DNMT1 | GNMT | ENSAPLP00000002034 | ENSAPLP00000025948 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Glycine N-methyltransferase. | 0.942 |
| DNMT1 | MAT1A | ENSAPLP00000002034 | ENSAPLP00000019358 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.903 |
| DNMT1 | MAT2A | ENSAPLP00000002034 | ENSAPLP00000031713 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.903 |
| DNMT1 | MAT2B | ENSAPLP00000002034 | ENSAPLP00000029552 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.924 |
| DNMT1 | U3IS18_ANAPP | ENSAPLP00000002034 | ENSAPLP00000010041 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.903 |
| ENSAPLP00000025202 | GNMT | ENSAPLP00000025202 | ENSAPLP00000025948 | Hcy-binding domain-containing protein. | Glycine N-methyltransferase. | 0.654 |
| ENSAPLP00000025202 | IL4I1 | ENSAPLP00000025202 | ENSAPLP00000015917 | Hcy-binding domain-containing protein. | Amine oxidase. | 0.901 |
| ENSAPLP00000025202 | MAT1A | ENSAPLP00000025202 | ENSAPLP00000019358 | Hcy-binding domain-containing protein. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.962 |
| ENSAPLP00000025202 | MAT2A | ENSAPLP00000025202 | ENSAPLP00000031713 | Hcy-binding domain-containing protein. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.962 |
| ENSAPLP00000025202 | MAT2B | ENSAPLP00000025202 | ENSAPLP00000029552 | Hcy-binding domain-containing protein. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.951 |
| ENSAPLP00000025202 | MTR | ENSAPLP00000025202 | ENSAPLP00000009750 | Hcy-binding domain-containing protein. | 5-methyltetrahydrofolate-homocysteine methyltransferase. | 0.965 |