Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POLR1ERNA polymerase I subunit E. (466 aa)    
Predicted Functional Partners:
POLR1C
RNA polymerase I and III subunit C.
   
 0.999
POLR1B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.999
POLR1A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.999
POLR2E
RNA polymerase II subunit E.
   
 0.997
POLR2F
RNA polymerase II subunit F.
   
 0.996
POLR2L
RNA polymerase II subunit L.
   
 0.994
POLR2H
RNA polymerase II subunit H.
   
 0.994
POLR2K
RNA polymerase II subunit K.
   
 0.993
POLR1D
RNA polymerase I and III subunit D.
   
 0.987
RRN3
RRN3 homolog, RNA polymerase I transcription factor.
   
 0.972
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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