GAN protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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Experiments

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[Homology]

Score

GAN

Gigaxonin. (597 aa)

Predicted Functional Partners:

CUL3

0.875

DES

0.846

SDC1

0.740

FABP5

0.663

RBX1

0.647

NEFL

0.640

U3IYV3_ANAPP

0.636

COMMD9

0.636

INA

0.623

ENSAPLP00000031820

0.623

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COMMD9	CUL3	ENSAPLP00000031232	ENSAPLP00000032353	COMM domain containing 9.	Cullin 3; Belongs to the cullin family.	0.555
COMMD9	GAN	ENSAPLP00000031232	ENSAPLP00000010075	COMM domain containing 9.	Gigaxonin.	0.636
COMMD9	RBX1	ENSAPLP00000031232	ENSAPLP00000010158	COMM domain containing 9.	Ring-box 1.	0.570
COMMD9	U3IYV3_ANAPP	ENSAPLP00000031232	ENSAPLP00000012429	COMM domain containing 9.	COMM domain-containing protein.	0.992
CUL3	COMMD9	ENSAPLP00000032353	ENSAPLP00000031232	Cullin 3; Belongs to the cullin family.	COMM domain containing 9.	0.555
CUL3	GAN	ENSAPLP00000032353	ENSAPLP00000010075	Cullin 3; Belongs to the cullin family.	Gigaxonin.	0.875
CUL3	RBX1	ENSAPLP00000032353	ENSAPLP00000010158	Cullin 3; Belongs to the cullin family.	Ring-box 1.	0.999
CUL3	U3IYV3_ANAPP	ENSAPLP00000032353	ENSAPLP00000012429	Cullin 3; Belongs to the cullin family.	COMM domain-containing protein.	0.557
DES	ENSAPLP00000031820	ENSAPLP00000027398	ENSAPLP00000031820	Desmin; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.436
DES	GAN	ENSAPLP00000027398	ENSAPLP00000010075	Desmin; Belongs to the intermediate filament family.	Gigaxonin.	0.846
DES	INA	ENSAPLP00000027398	ENSAPLP00000016478	Desmin; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.436
DES	NEFL	ENSAPLP00000027398	ENSAPLP00000017933	Desmin; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.855
ENSAPLP00000031820	DES	ENSAPLP00000031820	ENSAPLP00000027398	IF rod domain-containing protein; Belongs to the intermediate filament family.	Desmin; Belongs to the intermediate filament family.	0.436
ENSAPLP00000031820	GAN	ENSAPLP00000031820	ENSAPLP00000010075	IF rod domain-containing protein; Belongs to the intermediate filament family.	Gigaxonin.	0.623
ENSAPLP00000031820	INA	ENSAPLP00000031820	ENSAPLP00000016478	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.722
ENSAPLP00000031820	NEFL	ENSAPLP00000031820	ENSAPLP00000017933	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.773
FABP5	GAN	ENSAPLP00000024200	ENSAPLP00000010075	Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Gigaxonin.	0.663
FABP5	SDC1	ENSAPLP00000024200	ENSAPLP00000010205	Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.555
GAN	COMMD9	ENSAPLP00000010075	ENSAPLP00000031232	Gigaxonin.	COMM domain containing 9.	0.636
GAN	CUL3	ENSAPLP00000010075	ENSAPLP00000032353	Gigaxonin.	Cullin 3; Belongs to the cullin family.	0.875