STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1220 aa)    
Predicted Functional Partners:
CCBE1
Collagen and calcium binding EGF domains 1.
      
 0.749
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
   
  
 0.614
SLC35F1
Solute carrier family 35 member F1.
   
  
 0.588
FBN2
Fibrillin 2.
   
 0.587
ATP8B3
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.586
ATP13A3
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.545
CACNA1I
Calcium voltage-gated channel subunit alpha1 I.
      
 0.543
NOS2
Nitric oxide synthase; Produces nitric oxide (NO).
      
 0.536
DIO2
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.530
ADCY8
Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.514
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.