Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1220 aa)    
Predicted Functional Partners:
CCBE1
Collagen and calcium binding EGF domains 1.
      
 0.597
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
   
 
 0.555
PALD1
Phosphatase domain containing paladin 1.
      
 0.550
FBN2
Fibrillin 2.
   
 0.543
CX3CL1
SCY domain-containing protein.
    
 0.508
ENSAPLP00000027233
TGF_BETA_2 domain-containing protein.
      
 0.496
COP1
COP1 E3 ubiquitin ligase.
    
 0.492
VIPR1
G_PROTEIN_RECEP_F2_4 domain-containing protein.
      
 0.484
NEXMIF
Neurite extension and migration factor.
      
 0.484
TVP23A
Golgi apparatus membrane protein TVP23 homolog.
      
 0.482
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (14%) [HD]