STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF8IRF-3 domain-containing protein. (306 aa)    
Predicted Functional Partners:
BATF3
Basic leucine zipper ATF-like transcription factor 3.
   
 0.720
IRF1
Interferon regulatory factor 1.
   
 0.600
MAFB
MAF bZIP transcription factor B.
      
 0.576
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.565
CDC34
Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.535
ZBTB46
Uncharacterized protein.
    
 0.531
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 
 0.530
SPI1
Spi-1 proto-oncogene.
   
 
 0.519
XCR1
X-C motif chemokine receptor 1.
   
  
 0.503
TRAK1
Trafficking kinesin protein 1.
    
 
 0.493
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.