| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS1 | ATIC | ENSAPLP00000019532 | ENSAPLP00000014206 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.956 |
| ADSS1 | ENTPD4 | ENSAPLP00000019532 | ENSAPLP00000014700 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 0.667 |
| ADSS1 | ENTPD5 | ENSAPLP00000019532 | ENSAPLP00000013949 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. | 0.631 |
| ADSS1 | ITPA | ENSAPLP00000019532 | ENSAPLP00000017648 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine triphosphatase. | 0.794 |
| ADSS1 | NME6 | ENSAPLP00000019532 | ENSAPLP00000008746 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Nucleoside diphosphate kinase. | 0.621 |
| ADSS1 | NT5C1A | ENSAPLP00000019532 | ENSAPLP00000010254 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5'-nucleotidase, cytosolic IA. | 0.631 |
| ADSS1 | PPAT | ENSAPLP00000019532 | ENSAPLP00000008829 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.771 |
| ATIC | ADSS1 | ENSAPLP00000014206 | ENSAPLP00000019532 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.956 |
| ATIC | ENTPD4 | ENSAPLP00000014206 | ENSAPLP00000014700 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 0.477 |
| ATIC | ITPA | ENSAPLP00000014206 | ENSAPLP00000017648 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Inosine triphosphatase. | 0.487 |
| ATIC | NT5C1A | ENSAPLP00000014206 | ENSAPLP00000010254 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 5'-nucleotidase, cytosolic IA. | 0.616 |
| ATIC | PPAT | ENSAPLP00000014206 | ENSAPLP00000008829 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.988 |
| ATIC | TRIT1 | ENSAPLP00000014206 | ENSAPLP00000011205 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | tRNA isopentenyltransferase 1; Belongs to the IPP transferase family. | 0.538 |
| ENTPD4 | ADSS1 | ENSAPLP00000014700 | ENSAPLP00000019532 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.667 |
| ENTPD4 | ATIC | ENSAPLP00000014700 | ENSAPLP00000014206 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.477 |
| ENTPD4 | ENTPD5 | ENSAPLP00000014700 | ENSAPLP00000013949 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. | 0.488 |
| ENTPD4 | ITPA | ENSAPLP00000014700 | ENSAPLP00000017648 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | Inosine triphosphatase. | 0.653 |
| ENTPD4 | NME6 | ENSAPLP00000014700 | ENSAPLP00000008746 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | Nucleoside diphosphate kinase. | 0.663 |
| ENTPD4 | NT5C1A | ENSAPLP00000014700 | ENSAPLP00000010254 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 5'-nucleotidase, cytosolic IA. | 0.722 |
| ENTPD4 | PPAT | ENSAPLP00000014700 | ENSAPLP00000008829 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.551 |