| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO1 | AGO2 | ENSAPLP00000010217 | ENSAPLP00000010261 | Argonaute RISC component 1; Belongs to the argonaute family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.916 |
| AGO1 | DDX20 | ENSAPLP00000010217 | ENSAPLP00000013658 | Argonaute RISC component 1; Belongs to the argonaute family. | DEAD-box helicase 20; Belongs to the DEAD box helicase family. | 0.507 |
| AGO1 | DDX6 | ENSAPLP00000010217 | ENSAPLP00000006939 | Argonaute RISC component 1; Belongs to the argonaute family. | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | 0.785 |
| AGO1 | DICER1 | ENSAPLP00000010217 | ENSAPLP00000012230 | Argonaute RISC component 1; Belongs to the argonaute family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.940 |
| AGO1 | DROSHA | ENSAPLP00000010217 | ENSAPLP00000004055 | Argonaute RISC component 1; Belongs to the argonaute family. | Drosha ribonuclease III. | 0.846 |
| AGO1 | GEMIN4 | ENSAPLP00000010217 | ENSAPLP00000023160 | Argonaute RISC component 1; Belongs to the argonaute family. | Gem nuclear organelle associated protein 4. | 0.528 |
| AGO1 | TNRC6B | ENSAPLP00000010217 | ENSAPLP00000016504 | Argonaute RISC component 1; Belongs to the argonaute family. | Trinucleotide repeat containing adaptor 6B. | 0.677 |
| AGO1 | TNRC6C | ENSAPLP00000010217 | ENSAPLP00000005040 | Argonaute RISC component 1; Belongs to the argonaute family. | Trinucleotide repeat containing adaptor 6C. | 0.855 |
| AGO1 | TSNAX | ENSAPLP00000010217 | ENSAPLP00000013253 | Argonaute RISC component 1; Belongs to the argonaute family. | Uncharacterized protein. | 0.775 |
| AGO2 | AGO1 | ENSAPLP00000010261 | ENSAPLP00000010217 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Argonaute RISC component 1; Belongs to the argonaute family. | 0.916 |
| AGO2 | AGO3 | ENSAPLP00000010261 | ENSAPLP00000009447 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | 0.915 |
| AGO2 | DDX20 | ENSAPLP00000010261 | ENSAPLP00000013658 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DEAD-box helicase 20; Belongs to the DEAD box helicase family. | 0.937 |
| AGO2 | DDX6 | ENSAPLP00000010261 | ENSAPLP00000006939 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DEAD-box helicase 6; Belongs to the DEAD box helicase family. | 0.974 |
| AGO2 | DICER1 | ENSAPLP00000010261 | ENSAPLP00000012230 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.998 |
| AGO2 | DROSHA | ENSAPLP00000010261 | ENSAPLP00000004055 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Drosha ribonuclease III. | 0.928 |
| AGO2 | GEMIN4 | ENSAPLP00000010261 | ENSAPLP00000023160 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Gem nuclear organelle associated protein 4. | 0.940 |
| AGO2 | TNRC6B | ENSAPLP00000010261 | ENSAPLP00000016504 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat containing adaptor 6B. | 0.976 |
| AGO2 | TNRC6C | ENSAPLP00000010261 | ENSAPLP00000005040 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat containing adaptor 6C. | 0.991 |
| AGO2 | TSNAX | ENSAPLP00000010261 | ENSAPLP00000013253 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Uncharacterized protein. | 0.972 |
| AGO3 | AGO2 | ENSAPLP00000009447 | ENSAPLP00000010261 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.915 |
