STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDK3Protein-serine/threonine kinase. (406 aa)    
Predicted Functional Partners:
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.918
DLD
Dihydrolipoyl dehydrogenase.
   
 0.871
ENSAPLP00000024157
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.846
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.835
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.750
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
   
 
 0.667
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
 
 0.635
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
    
 0.628
PDP2
Pyruvate dehyrogenase phosphatase catalytic subunit 2.
   
 
 0.623
DLST
Dihydrolipoamide S-succinyltransferase.
    
 0.623
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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