| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABCD2 | ACOX1 | ENSAPLP00000013672 | ENSAPLP00000016006 | ATP binding cassette subfamily D member 2. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.581 |
| ABCD2 | ELOVL1 | ENSAPLP00000013672 | ENSAPLP00000010280 | ATP binding cassette subfamily D member 2. | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | 0.736 |
| ABCD2 | ELOVL7 | ENSAPLP00000013672 | ENSAPLP00000009372 | ATP binding cassette subfamily D member 2. | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] | 0.406 |
| ABCD2 | PEX7 | ENSAPLP00000013672 | ENSAPLP00000016136 | ATP binding cassette subfamily D member 2. | Peroxisomal biogenesis factor 7. | 0.670 |
| ACOX1 | ABCD2 | ENSAPLP00000016006 | ENSAPLP00000013672 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | ATP binding cassette subfamily D member 2. | 0.581 |
| ACOX1 | ACOX2 | ENSAPLP00000016006 | ENSAPLP00000030471 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.940 |
| ACOX1 | ELOVL1 | ENSAPLP00000016006 | ENSAPLP00000010280 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | 0.638 |
| ACOX1 | HSD17B12 | ENSAPLP00000016006 | ENSAPLP00000022442 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.634 |
| ACOX1 | PEX7 | ENSAPLP00000016006 | ENSAPLP00000016136 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Peroxisomal biogenesis factor 7. | 0.492 |
| ACOX2 | ACOX1 | ENSAPLP00000030471 | ENSAPLP00000016006 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.940 |
| ACOX2 | ELOVL1 | ENSAPLP00000030471 | ENSAPLP00000010280 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | 0.524 |
| ACOX2 | HSD17B12 | ENSAPLP00000030471 | ENSAPLP00000022442 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.519 |
| ACOX2 | PEX7 | ENSAPLP00000030471 | ENSAPLP00000016136 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Peroxisomal biogenesis factor 7. | 0.481 |
| ELOVL1 | ABCD2 | ENSAPLP00000010280 | ENSAPLP00000013672 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | ATP binding cassette subfamily D member 2. | 0.736 |
| ELOVL1 | ACOX1 | ENSAPLP00000010280 | ENSAPLP00000016006 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.638 |
| ELOVL1 | ACOX2 | ENSAPLP00000010280 | ENSAPLP00000030471 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.524 |
| ELOVL1 | ELOVL4 | ENSAPLP00000010280 | ENSAPLP00000005403 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] | 0.912 |
| ELOVL1 | ELOVL7 | ENSAPLP00000010280 | ENSAPLP00000009372 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] | 0.902 |
| ELOVL1 | HSD17B12 | ENSAPLP00000010280 | ENSAPLP00000022442 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.959 |
| ELOVL1 | MED16 | ENSAPLP00000010280 | ENSAPLP00000006459 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.537 |