KIAA0319 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

KIAA0319

KIAA0319. (1079 aa)

Predicted Functional Partners:

PSD2

0.690

CYP46A1

0.684

LPIN3

0.605

SH3GL2

0.604

AP1S3

0.603

AP2M1

0.577

DCDC2

0.564

C17orf75

0.548

DNAAF4

0.544

FDFT1

0.507

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1S3	AP2M1	ENSAPLP00000029283	ENSAPLP00000006303	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.631
AP1S3	CYP46A1	ENSAPLP00000029283	ENSAPLP00000004368	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	0.605
AP1S3	FDFT1	ENSAPLP00000029283	ENSAPLP00000023390	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.400
AP1S3	KIAA0319	ENSAPLP00000029283	ENSAPLP00000010332	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	KIAA0319.	0.603
AP1S3	LPIN3	ENSAPLP00000029283	ENSAPLP00000005551	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Lipin 3.	0.580
AP1S3	PSD2	ENSAPLP00000029283	ENSAPLP00000032197	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	SEC7 domain-containing protein.	0.602
AP1S3	SH3GL2	ENSAPLP00000029283	ENSAPLP00000006849	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	SH3 domain containing GRB2 like 2, endophilin A1.	0.702
AP2M1	AP1S3	ENSAPLP00000006303	ENSAPLP00000029283	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.631
AP2M1	KIAA0319	ENSAPLP00000006303	ENSAPLP00000010332	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	KIAA0319.	0.577
AP2M1	SH3GL2	ENSAPLP00000006303	ENSAPLP00000006849	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	SH3 domain containing GRB2 like 2, endophilin A1.	0.631
C17orf75	KIAA0319	ENSAPLP00000006993	ENSAPLP00000010332	Chromosome 17 open reading frame 75.	KIAA0319.	0.548
CYP46A1	AP1S3	ENSAPLP00000004368	ENSAPLP00000029283	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.605
CYP46A1	FDFT1	ENSAPLP00000004368	ENSAPLP00000023390	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.590
CYP46A1	KIAA0319	ENSAPLP00000004368	ENSAPLP00000010332	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	KIAA0319.	0.684
CYP46A1	LPIN3	ENSAPLP00000004368	ENSAPLP00000005551	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	Lipin 3.	0.605
CYP46A1	PSD2	ENSAPLP00000004368	ENSAPLP00000032197	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	SEC7 domain-containing protein.	0.684
CYP46A1	SH3GL2	ENSAPLP00000004368	ENSAPLP00000006849	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	SH3 domain containing GRB2 like 2, endophilin A1.	0.605
DCDC2	DNAAF4	ENSAPLP00000011755	ENSAPLP00000002721	Doublecortin domain containing 2.	Dynein axonemal assembly factor 4.	0.641
DCDC2	KIAA0319	ENSAPLP00000011755	ENSAPLP00000010332	Doublecortin domain containing 2.	KIAA0319.	0.564
DNAAF4	DCDC2	ENSAPLP00000002721	ENSAPLP00000011755	Dynein axonemal assembly factor 4.	Doublecortin domain containing 2.	0.641