Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (336 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.999
AXIN1
Axin 1.
    
 0.988
AXIN2
DIX domain-containing protein.
    
 0.988
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
   
0.987
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
 0.964
GRK3
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
 0.964
AMER1
APC membrane recruitment protein 1.
     
 0.945
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
0.940
ENSAPLP00000020785
RGS domain-containing protein.
    
 0.928
CRBN
Cereblon.
    
 
 0.919
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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