Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PDIA4Protein disulfide-isomerase. (647 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.993
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.990
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.984
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.978
CALR
Calreticulin.
   
 0.971
PDIA3
Protein disulfide-isomerase.
   
   0.963
HYOU1
Hypoxia up-regulated 1.
   
 0.958
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
0.946
CALR3
Calreticulin.
   
 0.909
PPIB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.897
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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