IGF1 protein (Anas platyrhynchos) - STRING interaction network

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Score

IGF1

Insulin like growth factor 1. (153 aa)

Predicted Functional Partners:

INS

0.952

IGFBP3

0.921

IGF1R

0.918

INSR

0.918

IGF2

0.905

EGFR

0.650

PDGFRA

0.650

KIT

0.650

RET

0.650

KDR

0.650

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	IGF1	ENSAPLP00000002564	ENSAPLP00000010417	Receptor protein-tyrosine kinase.	Insulin like growth factor 1.	0.650
EGFR	IGF1R	ENSAPLP00000002564	ENSAPLP00000008278	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.500
EGFR	IGF2	ENSAPLP00000002564	ENSAPLP00000020248	Receptor protein-tyrosine kinase.	Insulin like growth factor 2.	0.678
EGFR	INS	ENSAPLP00000002564	ENSAPLP00000012854	Receptor protein-tyrosine kinase.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.942
EGFR	INSR	ENSAPLP00000002564	ENSAPLP00000024270	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.500
EGFR	KDR	ENSAPLP00000002564	ENSAPLP00000005293	Receptor protein-tyrosine kinase.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.422
EGFR	PDGFRA	ENSAPLP00000002564	ENSAPLP00000003065	Receptor protein-tyrosine kinase.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.946
EGFR	RET	ENSAPLP00000002564	ENSAPLP00000004162	Receptor protein-tyrosine kinase.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.597
IGF1	EGFR	ENSAPLP00000010417	ENSAPLP00000002564	Insulin like growth factor 1.	Receptor protein-tyrosine kinase.	0.650
IGF1	IGF1R	ENSAPLP00000010417	ENSAPLP00000008278	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.918
IGF1	IGF2	ENSAPLP00000010417	ENSAPLP00000020248	Insulin like growth factor 1.	Insulin like growth factor 2.	0.905
IGF1	IGFBP3	ENSAPLP00000010417	ENSAPLP00000016279	Insulin like growth factor 1.	Insulin like growth factor binding protein 3.	0.921
IGF1	INS	ENSAPLP00000010417	ENSAPLP00000012854	Insulin like growth factor 1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.952
IGF1	INSR	ENSAPLP00000010417	ENSAPLP00000024270	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.918
IGF1	KDR	ENSAPLP00000010417	ENSAPLP00000005293	Insulin like growth factor 1.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.650
IGF1	KIT	ENSAPLP00000010417	ENSAPLP00000003686	Insulin like growth factor 1.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.650
IGF1	PDGFRA	ENSAPLP00000010417	ENSAPLP00000003065	Insulin like growth factor 1.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.650
IGF1	RET	ENSAPLP00000010417	ENSAPLP00000004162	Insulin like growth factor 1.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.650
IGF1R	EGFR	ENSAPLP00000008278	ENSAPLP00000002564	Tyrosine-protein kinase receptor.	Receptor protein-tyrosine kinase.	0.500
IGF1R	IGF1	ENSAPLP00000008278	ENSAPLP00000010417	Tyrosine-protein kinase receptor.	Insulin like growth factor 1.	0.918