STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1863 aa)    
Predicted Functional Partners:
CRK
CRK proto-oncogene, adaptor protein.
    
 0.996
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.973
ELMO2
Engulfment and cell motility 2.
    
 0.962
RAC1
Rac family small GTPase 1.
   
 0.952
RAC3
Rac family small GTPase 3.
   
 0.952
RAC2
Rac family small GTPase 2.
   
 0.952
PTK2
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.920
ELMO1-2
Engulfment and cell motility 1.
    
 0.761
ELMO3
Engulfment and cell motility 3.
    
 0.718
RHOG-2
Uncharacterized protein.
   
 0.716
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.