Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1863 aa)    
Predicted Functional Partners:
CRK
CRK proto-oncogene, adaptor protein.
    
 0.981
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.970
ELMO2
Engulfment and cell motility 2.
   
 0.966
RAC2
Rac family small GTPase 2.
   
 0.952
RAC1
Rac family small GTPase 1.
   
 0.951
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.941
PTK2
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.921
RHOG-2
Uncharacterized protein.
   
 0.766
RHOG
Ras homolog family member G.
   
 0.766
ELMO1-2
Engulfment and cell motility 1.
   
 0.685
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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