Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NUDCNuclear distribution C, dynein complex regulator. (341 aa)    
Predicted Functional Partners:
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
   
 0.996
PLK1
Serine/threonine-protein kinase PLK.
   
 0.983
MAPRE1
Microtubule associated protein RP/EB family member 1.
   
 
 0.977
SGO1
Shugoshin 1.
     
 0.974
NDE1
NudE neurodevelopment protein 1.
     
 0.965
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
     
 0.961
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.952
U3J5S8_ANAPP
Uncharacterized protein.
     
 0.951
RCC2
Regulator of chromosome condensation 2.
   
  0.948
MAD1L1
Mitotic arrest deficient 1 like 1.
    
  0.944
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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