ARHGEF11 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ARHGEF11

RGS domain-containing protein. (576 aa)

Predicted Functional Partners:

ENSAPLP00000030426

0.925

GNA13

0.851

GNA12

0.804

RHOA

0.719

RHOC

0.719

RHOB

0.719

RND1

0.665

RND3

0.665

CDC42

0.658

PLXNB2

0.631

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF11	CDC42	ENSAPLP00000010461	ENSAPLP00000021122	RGS domain-containing protein.	Cell division cycle 42.	0.658
ARHGEF11	ENSAPLP00000030426	ENSAPLP00000010461	ENSAPLP00000030426	RGS domain-containing protein.	DH domain-containing protein.	0.925
ARHGEF11	GNA12	ENSAPLP00000010461	ENSAPLP00000003108	RGS domain-containing protein.	G protein subunit alpha 12.	0.804
ARHGEF11	GNA13	ENSAPLP00000010461	ENSAPLP00000024986	RGS domain-containing protein.	G protein subunit alpha 13.	0.851
ARHGEF11	PLXNB2	ENSAPLP00000010461	ENSAPLP00000004607	RGS domain-containing protein.	Plexin B2.	0.631
ARHGEF11	RHOA	ENSAPLP00000010461	ENSAPLP00000014536	RGS domain-containing protein.	Ras homolog family member A.	0.719
ARHGEF11	RHOB	ENSAPLP00000010461	ENSAPLP00000019696	RGS domain-containing protein.	Ras homolog family member B.	0.719
ARHGEF11	RHOC	ENSAPLP00000010461	ENSAPLP00000019250	RGS domain-containing protein.	Uncharacterized protein.	0.719
ARHGEF11	RND1	ENSAPLP00000010461	ENSAPLP00000002622	RGS domain-containing protein.	Rho family GTPase 1.	0.665
ARHGEF11	RND3	ENSAPLP00000010461	ENSAPLP00000006383	RGS domain-containing protein.	Rho family GTPase 3.	0.665
CDC42	ARHGEF11	ENSAPLP00000021122	ENSAPLP00000010461	Cell division cycle 42.	RGS domain-containing protein.	0.658
CDC42	ENSAPLP00000030426	ENSAPLP00000021122	ENSAPLP00000030426	Cell division cycle 42.	DH domain-containing protein.	0.658
CDC42	GNA12	ENSAPLP00000021122	ENSAPLP00000003108	Cell division cycle 42.	G protein subunit alpha 12.	0.504
CDC42	GNA13	ENSAPLP00000021122	ENSAPLP00000024986	Cell division cycle 42.	G protein subunit alpha 13.	0.578
CDC42	RHOA	ENSAPLP00000021122	ENSAPLP00000014536	Cell division cycle 42.	Ras homolog family member A.	0.536
CDC42	RHOB	ENSAPLP00000021122	ENSAPLP00000019696	Cell division cycle 42.	Ras homolog family member B.	0.536
CDC42	RHOC	ENSAPLP00000021122	ENSAPLP00000019250	Cell division cycle 42.	Uncharacterized protein.	0.536
CDC42	RND1	ENSAPLP00000021122	ENSAPLP00000002622	Cell division cycle 42.	Rho family GTPase 1.	0.432
CDC42	RND3	ENSAPLP00000021122	ENSAPLP00000006383	Cell division cycle 42.	Rho family GTPase 3.	0.432
ENSAPLP00000030426	ARHGEF11	ENSAPLP00000030426	ENSAPLP00000010461	DH domain-containing protein.	RGS domain-containing protein.	0.925