Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
U3ITA2_ANAPPBH4_AAA_HYDROXYL_2 domain-containing protein. (457 aa)    
Predicted Functional Partners:
DDC
Dopa decarboxylase.
   
 0.965
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.964
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
  
 0.964
GOT2
Aspartate aminotransferase.
  
 
 0.932
GOT1
Aspartate aminotransferase.
  
 
 0.927
SPR
Uncharacterized protein.
     
 0.926
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.926
IL4I1
Amine oxidase.
     
 0.915
TPO
Thyroid peroxidase.
     
 0.914
U3IIA3_ANAPP
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.906
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (18%) [HD]