| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS1 | ADSS2 | ENSAPLP00000019532 | ENSAPLP00000011632 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.997 |
| ADSS1 | ASL | ENSAPLP00000019532 | ENSAPLP00000028978 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Lyase_1 domain-containing protein. | 0.629 |
| ADSS1 | ASNS | ENSAPLP00000019532 | ENSAPLP00000016213 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.929 |
| ADSS1 | ASS1 | ENSAPLP00000019532 | ENSAPLP00000010477 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.937 |
| ADSS1 | ENSAPLP00000022138 | ENSAPLP00000019532 | ENSAPLP00000022138 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Glutamine amidotransferase type-1 domain-containing protein. | 0.933 |
| ADSS1 | ENSAPLP00000023817 | ENSAPLP00000019532 | ENSAPLP00000023817 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.401 |
| ADSS2 | ADSS1 | ENSAPLP00000011632 | ENSAPLP00000019532 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.997 |
| ADSS2 | ASL | ENSAPLP00000011632 | ENSAPLP00000028978 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Lyase_1 domain-containing protein. | 0.629 |
| ADSS2 | ASNS | ENSAPLP00000011632 | ENSAPLP00000016213 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.929 |
| ADSS2 | ASS1 | ENSAPLP00000011632 | ENSAPLP00000010477 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.952 |
| ADSS2 | ENSAPLP00000022138 | ENSAPLP00000011632 | ENSAPLP00000022138 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Glutamine amidotransferase type-1 domain-containing protein. | 0.933 |
| ADSS2 | ENSAPLP00000023817 | ENSAPLP00000011632 | ENSAPLP00000023817 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.548 |
| ASL | ADSS1 | ENSAPLP00000028978 | ENSAPLP00000019532 | Lyase_1 domain-containing protein. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.629 |
| ASL | ADSS2 | ENSAPLP00000028978 | ENSAPLP00000011632 | Lyase_1 domain-containing protein. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.629 |
| ASL | ASNS | ENSAPLP00000028978 | ENSAPLP00000016213 | Lyase_1 domain-containing protein. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.406 |
| ASL | ASS1 | ENSAPLP00000028978 | ENSAPLP00000010477 | Lyase_1 domain-containing protein. | Uncharacterized protein. | 0.997 |
| ASL | CPS1 | ENSAPLP00000028978 | ENSAPLP00000002003 | Lyase_1 domain-containing protein. | Carbamoyl-phosphate synthase 1. | 0.777 |
| ASL | ENSAPLP00000022138 | ENSAPLP00000028978 | ENSAPLP00000022138 | Lyase_1 domain-containing protein. | Glutamine amidotransferase type-1 domain-containing protein. | 0.680 |
| ASL | ENSAPLP00000023817 | ENSAPLP00000028978 | ENSAPLP00000023817 | Lyase_1 domain-containing protein. | Uncharacterized protein. | 0.961 |
| ASL | NOS1 | ENSAPLP00000028978 | ENSAPLP00000012568 | Lyase_1 domain-containing protein. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.938 |