STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (670 aa)    
Predicted Functional Partners:
U3IIW0_ANAPP
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
  
  
 
0.901
DRD4
Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.752
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 
 0.687
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
      
 0.644
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.638
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.608
TXNDC12
Thioredoxin domain containing 12.
      
 0.606
B3GAT2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.
   
  
 0.605
EXTL3
Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
      
 0.586
HTR2A
5-hydroxytryptamine receptor 2A.
      
 0.580
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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