STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (670 aa)    
Predicted Functional Partners:
TPH2
Tryptophan hydroxylase 2.
      
 0.747
DRD4
Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.
    
 0.726
CNR1
Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.634
MAOA
Amine oxidase.
      
 0.611
U3IYQ3_ANAPP
Amine oxidase.
      
 0.586
HTR1A
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.568
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.566
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
      
 0.526
SLC17A8
Solute carrier family 17 member 8.
   
  
 0.482
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
    
 0.480
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.