Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PRPF39Pre-mRNA processing factor 39. (674 aa)    
Predicted Functional Partners:
TRNAU1AP
tRNA selenocysteine 1 associated protein 1.
   
 
 0.927
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.919
PNISR
PNN interacting serine and arginine rich protein.
   
  
 0.896
SNRPF
Small nuclear ribonucleoprotein polypeptide F.
    
 0.888
SNRPD1
Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.
    
 0.871
SNRNP35
Small nuclear ribonucleoprotein U11/U12 subunit 35.
   
 
 0.860
SF3B1
Splicing factor 3b subunit 1.
   
 
 0.844
LUC7L
LUC7 like.
   
 0.829
ENSAPLP00000019050
Uncharacterized protein.
   
 0.829
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.828
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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