STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKS2Poly [ADP-ribose] polymerase. (1109 aa)    
Predicted Functional Partners:
RNF146
Ring finger protein 146.
    
 0.922
AXIN1
Axin 1.
    
 0.922
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
    
 
 0.852
AXIN2
DIX domain-containing protein.
    
 0.844
ENSAPLP00000020785
RGS domain-containing protein.
    
 0.844
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.831
TERF1
Telomeric repeat binding factor 1.
    
 0.820
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.640
PARP3
Poly [ADP-ribose] polymerase.
   
 
 0.618
U3I9N3_ANAPP
Uncharacterized protein.
   
 0.616
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.