KLB protein (Anas platyrhynchos) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

Experiments

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[Homology]

Score

KLB

Klotho beta. (1006 aa)

Predicted Functional Partners:

FGF23

0.941

FGF19

0.875

FGFR4

0.835

FGFR1

0.830

FGFR2

0.702

FGFR3

0.699

TRPV6

0.603

PTH

0.595

GALNT3

0.553

YDJC

0.537

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF19	FGF23	ENSAPLP00000003785	ENSAPLP00000002493	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.688
FGF19	FGFR1	ENSAPLP00000003785	ENSAPLP00000013938	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.913
FGF19	FGFR2	ENSAPLP00000003785	ENSAPLP00000030490	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.950
FGF19	FGFR3	ENSAPLP00000003785	ENSAPLP00000032569	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.948
FGF19	FGFR4	ENSAPLP00000003785	ENSAPLP00000026950	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.982
FGF19	KLB	ENSAPLP00000003785	ENSAPLP00000011106	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Klotho beta.	0.875
FGF23	FGF19	ENSAPLP00000002493	ENSAPLP00000003785	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.688
FGF23	FGFR1	ENSAPLP00000002493	ENSAPLP00000013938	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.925
FGF23	FGFR2	ENSAPLP00000002493	ENSAPLP00000030490	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.972
FGF23	FGFR3	ENSAPLP00000002493	ENSAPLP00000032569	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.957
FGF23	FGFR4	ENSAPLP00000002493	ENSAPLP00000026950	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.907
FGF23	GALNT3	ENSAPLP00000002493	ENSAPLP00000013584	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Polypeptide N-acetylgalactosaminyltransferase.	0.796
FGF23	KLB	ENSAPLP00000002493	ENSAPLP00000011106	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Klotho beta.	0.941
FGF23	PTH	ENSAPLP00000002493	ENSAPLP00000004644	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.764
FGFR1	FGF19	ENSAPLP00000013938	ENSAPLP00000003785	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.913
FGFR1	FGF23	ENSAPLP00000013938	ENSAPLP00000002493	Fibroblast growth factor receptor.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.925
FGFR1	FGFR3	ENSAPLP00000013938	ENSAPLP00000032569	Fibroblast growth factor receptor.	Fibroblast growth factor receptor.	0.487
FGFR1	FGFR4	ENSAPLP00000013938	ENSAPLP00000026950	Fibroblast growth factor receptor.	Fibroblast growth factor receptor.	0.520
FGFR1	KLB	ENSAPLP00000013938	ENSAPLP00000011106	Fibroblast growth factor receptor.	Klotho beta.	0.830
FGFR2	FGF19	ENSAPLP00000030490	ENSAPLP00000003785	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.950