STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.985
TIRAP
TIR domain containing adaptor protein.
   
0.963
TOLLIP
Toll interacting protein.
    
 0.922
TLR6
Toll like receptor 6; Belongs to the Toll-like receptor family.
  
  
0.918
RAC1
Rac family small GTPase 1.
   
 0.914
TLR4
Toll like receptor 4.
   
0.841
LY96
Lymphocyte antigen 96.
   
 0.676
LY86
Lymphocyte antigen 86.
   
 0.668
IL6
Uncharacterized protein.
   
  
 0.667
HMGB1
High mobility group box 1.
    
 0.660
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.