U3IV88_ANAPP protein (Anas platyrhynchos) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

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Score

U3IV88_ANAPP

G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)

Predicted Functional Partners:

NPY

0.973

PYY

0.731

FAM13B

0.636

NME5

0.622

KCNS3

0.611

RUFY1

0.611

HNRNPAB

0.611

ENSAPLP00000018664

0.589

ENSAPLP00000032265

0.587

PNLDC1

0.555

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000018664	PYY	ENSAPLP00000018664	ENSAPLP00000018906	Uncharacterized protein.	Peptide YY.	0.624
ENSAPLP00000018664	U3IV88_ANAPP	ENSAPLP00000018664	ENSAPLP00000011161	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.589
ENSAPLP00000032265	FAM13B	ENSAPLP00000032265	ENSAPLP00000016982	dNK domain-containing protein.	Family with sequence similarity 13 member B.	0.601
ENSAPLP00000032265	HNRNPAB	ENSAPLP00000032265	ENSAPLP00000013867	dNK domain-containing protein.	Heterogeneous nuclear ribonucleoprotein A/B.	0.429
ENSAPLP00000032265	NME5	ENSAPLP00000032265	ENSAPLP00000013757	dNK domain-containing protein.	NME/NM23 family member 5; Belongs to the NDK family.	0.623
ENSAPLP00000032265	RUFY1	ENSAPLP00000032265	ENSAPLP00000010582	dNK domain-containing protein.	RUN and FYVE domain containing 1.	0.479
ENSAPLP00000032265	U3IV88_ANAPP	ENSAPLP00000032265	ENSAPLP00000011161	dNK domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.587
FAM13B	ENSAPLP00000032265	ENSAPLP00000016982	ENSAPLP00000032265	Family with sequence similarity 13 member B.	dNK domain-containing protein.	0.601
FAM13B	HNRNPAB	ENSAPLP00000016982	ENSAPLP00000013867	Family with sequence similarity 13 member B.	Heterogeneous nuclear ribonucleoprotein A/B.	0.611
FAM13B	NME5	ENSAPLP00000016982	ENSAPLP00000013757	Family with sequence similarity 13 member B.	NME/NM23 family member 5; Belongs to the NDK family.	0.761
FAM13B	RUFY1	ENSAPLP00000016982	ENSAPLP00000010582	Family with sequence similarity 13 member B.	RUN and FYVE domain containing 1.	0.612
FAM13B	U3IV88_ANAPP	ENSAPLP00000016982	ENSAPLP00000011161	Family with sequence similarity 13 member B.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.636
HNRNPAB	ENSAPLP00000032265	ENSAPLP00000013867	ENSAPLP00000032265	Heterogeneous nuclear ribonucleoprotein A/B.	dNK domain-containing protein.	0.429
HNRNPAB	FAM13B	ENSAPLP00000013867	ENSAPLP00000016982	Heterogeneous nuclear ribonucleoprotein A/B.	Family with sequence similarity 13 member B.	0.611
HNRNPAB	NME5	ENSAPLP00000013867	ENSAPLP00000013757	Heterogeneous nuclear ribonucleoprotein A/B.	NME/NM23 family member 5; Belongs to the NDK family.	0.616
HNRNPAB	RUFY1	ENSAPLP00000013867	ENSAPLP00000010582	Heterogeneous nuclear ribonucleoprotein A/B.	RUN and FYVE domain containing 1.	0.586
HNRNPAB	U3IV88_ANAPP	ENSAPLP00000013867	ENSAPLP00000011161	Heterogeneous nuclear ribonucleoprotein A/B.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.611
KCNS3	PNLDC1	ENSAPLP00000001255	ENSAPLP00000006629	Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family.	PARN like, ribonuclease domain containing 1.	0.443
KCNS3	U3IV88_ANAPP	ENSAPLP00000001255	ENSAPLP00000011161	Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.611
NME5	ENSAPLP00000032265	ENSAPLP00000013757	ENSAPLP00000032265	NME/NM23 family member 5; Belongs to the NDK family.	dNK domain-containing protein.	0.623

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.814

expected number of edges:

31

PPI enrichment p-value:

0.42

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009102

Biotin biosynthetic process

4 of 6

2.29

2.43

2.01e-05

GO:0072330

Monocarboxylic acid biosynthetic process

5 of 30

1.68

1.98

2.19e-05

GO:0046394

Carboxylic acid biosynthetic process

6 of 107

1.21

1.17

0.00022

GO:0044281

Small molecule metabolic process

7 of 429

0.67

0.46

0.0126

GO:0071704

Organic substance metabolic process

10 of 1181

0.39

0.28

0.0258

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36584052

(2022) The inside scoop: Comparative genomics of two intranuclear bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella aquae.

4 of 114

1.01

0.78

0.0028

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1111

Biotin metabolic process

4 of 5

2.37

2.7

6.44e-06

CL:1034

Mixed, incl. Vitamin biosynthetic process, and Coenzyme A metabolic process

5 of 45

1.51

1.59

9.73e-05

CL:842

Small molecule biosynthetic process, and Nucleotide biosynthetic process

6 of 141

1.09

0.97

0.00055

CL:1311

Phosphopantetheine, and Fatty acid synthase activity

2 of 5

2.06

0.85

0.0254

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00780

Biotin metabolism

5 of 26

1.75

2.32

3.19e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0093

Biotin biosynthesis

2 of 3

2.29

0.9

0.0221

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