STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM1Isthmin 1. (458 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
 
 
 0.910
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.729
SORD
Sorbitol dehydrogenase.
  
 
 0.673
ARHGAP20
Uncharacterized protein.
      
 0.631
SPTSSB
Serine palmitoyltransferase small subunit B.
    
 0.630
CLIC6
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.630
ORMDL2
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.559
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.559
ORMDL1
ORMDL sphingolipid biosynthesis regulator 1.
    
 
 0.559
SDR42E1
Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family.
  
 
 0.558
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.