STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY2Sprouty RTK signaling antagonist 2. (309 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.977
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.926
CBLB
Cbl proto-oncogene B.
    
 0.900
GRB2
Growth factor receptor bound protein 2.
    
 0.859
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.689
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.651
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
  
 0.642
FGFR1
Fibroblast growth factor receptor.
    
 
 0.614
FGF10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.613
ETV5
ETS domain-containing protein.
      
 0.586
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.