STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (701 aa)    
Predicted Functional Partners:
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
   
 0.993
ENSAPLP00000020757
Uncharacterized protein.
    
 0.987
ENSAPLP00000024521
EH domain-containing protein.
    
 0.987
ENSAPLP00000028453
annotation not available
    
 0.987
ENSAPLP00000028515
Uncharacterized protein.
    
 0.987
ITSN2
Uncharacterized protein.
    
 0.987
GAK
Cyclin G associated kinase.
   
 0.968
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.964
AP1G1
AP-1 complex subunit gamma.
   
 0.942
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 0.941
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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