STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN22Protein tyrosine phosphatase non-receptor type 22. (803 aa)    
Predicted Functional Partners:
CSK
Uncharacterized protein.
   
 0.974
LYN
Tyrosine-protein kinase.
   
 0.772
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.734
MATK
Tyrosine-protein kinase.
   
 0.702
BLK
Tyrosine-protein kinase.
   
 0.696
CD4
Ig-like domain-containing protein.
   
 0.670
CD247
CD247 molecule.
   
 0.664
SHC1
SHC adaptor protein 1.
    
 0.647
SHC3
SHC adaptor protein 3.
    
 0.647
ZAP70
Tyrosine-protein kinase.
   
 0.621
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.