STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL6STInterleukin 6 signal transducer. (933 aa)    
Predicted Functional Partners:
IL6
Uncharacterized protein.
    
 0.997
CNTF
Ciliary neurotrophic factor.
    
 0.991
JAK1
Tyrosine-protein kinase.
    
 0.974
IL6R
Interleukin 6 receptor.
   
 0.964
LIF
LIF interleukin 6 family cytokine.
    
 0.917
CNTFR
Ciliary neurotrophic factor receptor.
   
0.916
EBI3
Epstein-Barr virus induced 3.
   
 0.834
LIFR
LIF receptor subunit alpha.
    
0.808
ENSAPLP00000032274
Protein kinase domain-containing protein.
    
 0.775
JAK3
Uncharacterized protein.
    
 0.733
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.