STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HPS6HPS6 biogenesis of lysosomal organelles complex 2 subunit 3. (796 aa)    
Predicted Functional Partners:
HPS3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
   
 0.874
MIA3
MIA SH3 domain ER export factor 3.
      
 0.748
SZT2
Uncharacterized protein.
      
 0.747
HPS5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
    
 0.718
BLOC1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
     
 0.684
BLOC1S4
Biogenesis of lysosomal organelles complex 1 subunit 4.
     
 0.662
BROX
BRO1 domain and CAAX motif containing.
      
 0.645
GTF2H1
General transcription factor IIH subunit 1.
      
 0.611
NOLC1
Nucleolar and coiled-body phosphoprotein 1.
      
 0.611
MOSPD1
Motile sperm domain containing 1.
      
 0.611
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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