STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATMNon-specific serine/threonine protein kinase. (2967 aa)    
Predicted Functional Partners:
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.998
BRCA1
BRCA1 DNA repair associated.
    
 0.997
MRE11
MRE11 homolog, double strand break repair nuclease.
   
 0.996
ATR
Uncharacterized protein.
   
 0.994
U3I2H1_ANAPP
Uncharacterized protein.
   
 0.981
CHEK1
Checkpoint kinase 1.
    
 0.977
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.973
XRCC6
X-ray repair cross complementing 6.
    
 0.967
PAXIP1
PAX interacting protein 1.
   
 0.958
SQSTM1
Uncharacterized protein.
     
 0.957
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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