STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)    
Predicted Functional Partners:
IFNGR1
Interferon gamma receptor 1.
    
 0.998
IFNGR2
Interferon gamma receptor 2.
    
 0.998
IL10
Interleukin 10.
   
  
 0.974
ENSAPLP00000028410
Uncharacterized protein.
     
 0.970
IFNAR1
Interferon alpha and beta receptor subunit 1.
     
 0.961
IL6
Uncharacterized protein.
   
  
 0.959
IL4
Uncharacterized protein.
   
  
 0.958
CD4
Ig-like domain-containing protein.
   
  
 0.958
IFNAR2
Uncharacterized protein.
  
 
 0.954
IL-17
Uncharacterized protein.
   
  
 0.948
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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