STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBA3Ubiquitin like modifier activating enzyme 3. (442 aa)    
Predicted Functional Partners:
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
   
0.999
UBE2F
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.987
TRIP12
Thyroid hormone receptor interactor 12.
    
 0.962
BIRC6
Baculoviral IAP repeat containing 6.
  
 0.940
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 
 0.937
KDM2A
Lysine demethylase 2A.
    
 0.856
KDM2B
Lysine demethylase 2B.
    
 0.856
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.851
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.847
RBX1
Ring-box 1.
   
 0.840
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.