SPRTN protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPRTN

SprT-like N-terminal domain. (509 aa)

Predicted Functional Partners:

PCNA

0.933

VCP

0.867

U3I9N3_ANAPP

0.799

PTEN

0.799

PPP2R3A

0.775

PPP2R3B

0.775

SPATA5L1

0.755

SPATA5

0.755

UFD1

0.728

RFC1

0.713

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PCNA	RFC1	ENSAPLP00000028238	ENSAPLP00000010416	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C subunit 1.	0.992
PCNA	SPATA5	ENSAPLP00000028238	ENSAPLP00000006775	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Spermatogenesis associated 5.	0.615
PCNA	SPATA5L1	ENSAPLP00000028238	ENSAPLP00000003723	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Spermatogenesis associated 5 like 1.	0.615
PCNA	SPRTN	ENSAPLP00000028238	ENSAPLP00000013129	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	SprT-like N-terminal domain.	0.933
PCNA	UFD1	ENSAPLP00000028238	ENSAPLP00000019196	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin recognition factor in ER associated degradation 1.	0.715
PCNA	VCP	ENSAPLP00000028238	ENSAPLP00000004138	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.636
PPP2R3A	SPRTN	ENSAPLP00000002258	ENSAPLP00000013129	EF-hand domain-containing protein.	SprT-like N-terminal domain.	0.775
PPP2R3B	SPRTN	ENSAPLP00000012759	ENSAPLP00000013129	Uncharacterized protein.	SprT-like N-terminal domain.	0.775
PTEN	SPRTN	ENSAPLP00000015564	ENSAPLP00000013129	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	SprT-like N-terminal domain.	0.799
RFC1	PCNA	ENSAPLP00000010416	ENSAPLP00000028238	Replication factor C subunit 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.992
RFC1	SPATA5	ENSAPLP00000010416	ENSAPLP00000006775	Replication factor C subunit 1.	Spermatogenesis associated 5.	0.543
RFC1	SPATA5L1	ENSAPLP00000010416	ENSAPLP00000003723	Replication factor C subunit 1.	Spermatogenesis associated 5 like 1.	0.543
RFC1	SPRTN	ENSAPLP00000010416	ENSAPLP00000013129	Replication factor C subunit 1.	SprT-like N-terminal domain.	0.713
RFC1	UFD1	ENSAPLP00000010416	ENSAPLP00000019196	Replication factor C subunit 1.	Ubiquitin recognition factor in ER associated degradation 1.	0.606
RFC1	VCP	ENSAPLP00000010416	ENSAPLP00000004138	Replication factor C subunit 1.	Valosin containing protein; Belongs to the AAA ATPase family.	0.573
SPATA5	PCNA	ENSAPLP00000006775	ENSAPLP00000028238	Spermatogenesis associated 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.615
SPATA5	RFC1	ENSAPLP00000006775	ENSAPLP00000010416	Spermatogenesis associated 5.	Replication factor C subunit 1.	0.543
SPATA5	SPRTN	ENSAPLP00000006775	ENSAPLP00000013129	Spermatogenesis associated 5.	SprT-like N-terminal domain.	0.755
SPATA5	UFD1	ENSAPLP00000006775	ENSAPLP00000019196	Spermatogenesis associated 5.	Ubiquitin recognition factor in ER associated degradation 1.	0.906
SPATA5L1	PCNA	ENSAPLP00000003723	ENSAPLP00000028238	Spermatogenesis associated 5 like 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.615