STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITRM1Pitrilysin metallopeptidase 1. (1033 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 
 0.822
MIPEP
Mitochondrial intermediate peptidase.
    
 
 0.613
APLP2
Amyloid beta precursor like protein 2.
    
 
 0.598
FXN
Frataxin.
     
 0.593
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
   0.592
HSPD1
Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family.
   
 
  0.592
ATF6
Activating transcription factor 6.
   
    0.567
DLD
Dihydrolipoyl dehydrogenase.
   
 
 0.560
ATP5F1B
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
 0.556
EPRS1
Glutamyl-prolyl-tRNA synthetase.
  
  
 0.554
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.