STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (725 aa)    
Predicted Functional Partners:
STING1
Transmembrane protein 173.
   
 0.988
TANK
TRAF family member associated NFKB activator.
   
 0.987
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.987
U3IMS8_ANAPP
Uncharacterized protein; Belongs to the peptidase C19 family.
   
 0.957
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
   
 0.957
STAT1
Signal transducer and activator of transcription.
   
 0.946
IRF7
Interferon regulatory factor 7.
   
 0.938
TBK1
TANK binding kinase 1.
  
  
 
0.922
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.863
OPTN
Optineurin.
   
 0.854
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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