STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (880 aa)    
Predicted Functional Partners:
UBE2L3
Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.941
PSMD4
Proteasome 26S subunit, non-ATPase 4.
    
 
 0.878
MTDH
Metadherin.
      
 0.709
PSMD14
Proteasome 26S subunit, non-ATPase 14.
    
 
 0.693
ATP10A
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
 
  
 
 0.690
TRIP12
Thyroid hormone receptor interactor 12.
   
 
0.672
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 0.664
ENSAPLP00000026623
STI1 domain-containing protein.
   
 0.664
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 
 0.634
IGF2R
Insulin like growth factor 2 receptor.
   
  
 0.613
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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