RHOA protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RHOA

Ras homolog family member A. (193 aa)

Predicted Functional Partners:

ROCK1

0.991

ROCK2

0.987

ARHGAP35

0.980

ARHGEF18

0.974

DAAM1

0.973

PKN2

0.972

ARHGAP5

0.971

DIAPH2

0.967

ENSAPLP00000020757

0.965

ENSAPLP00000024521

0.965

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	ARHGAP5	ENSAPLP00000002344	ENSAPLP00000015220	Rho GTPase activating protein 35.	Rho GTPase activating protein 5.	0.900
ARHGAP35	RHOA	ENSAPLP00000002344	ENSAPLP00000014536	Rho GTPase activating protein 35.	Ras homolog family member A.	0.980
ARHGAP5	ARHGAP35	ENSAPLP00000015220	ENSAPLP00000002344	Rho GTPase activating protein 5.	Rho GTPase activating protein 35.	0.900
ARHGAP5	RHOA	ENSAPLP00000015220	ENSAPLP00000014536	Rho GTPase activating protein 5.	Ras homolog family member A.	0.971
ARHGEF18	ENSAPLP00000020757	ENSAPLP00000015636	ENSAPLP00000020757	Uncharacterized protein.	Uncharacterized protein.	0.426
ARHGEF18	ENSAPLP00000024521	ENSAPLP00000015636	ENSAPLP00000024521	Uncharacterized protein.	EH domain-containing protein.	0.426
ARHGEF18	RHOA	ENSAPLP00000015636	ENSAPLP00000014536	Uncharacterized protein.	Ras homolog family member A.	0.974
ARHGEF18	ROCK2	ENSAPLP00000015636	ENSAPLP00000029796	Uncharacterized protein.	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.481
DAAM1	DIAPH2	ENSAPLP00000031034	ENSAPLP00000029512	Dishevelled associated activator of morphogenesis 1.	Diaphanous related formin 2.	0.549
DAAM1	PKN2	ENSAPLP00000031034	ENSAPLP00000014628	Dishevelled associated activator of morphogenesis 1.	Protein kinase N2.	0.414
DAAM1	RHOA	ENSAPLP00000031034	ENSAPLP00000014536	Dishevelled associated activator of morphogenesis 1.	Ras homolog family member A.	0.973
DAAM1	ROCK1	ENSAPLP00000031034	ENSAPLP00000032159	Dishevelled associated activator of morphogenesis 1.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.557
DAAM1	ROCK2	ENSAPLP00000031034	ENSAPLP00000029796	Dishevelled associated activator of morphogenesis 1.	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.673
DIAPH2	DAAM1	ENSAPLP00000029512	ENSAPLP00000031034	Diaphanous related formin 2.	Dishevelled associated activator of morphogenesis 1.	0.549
DIAPH2	RHOA	ENSAPLP00000029512	ENSAPLP00000014536	Diaphanous related formin 2.	Ras homolog family member A.	0.967
DIAPH2	ROCK1	ENSAPLP00000029512	ENSAPLP00000032159	Diaphanous related formin 2.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.456
DIAPH2	ROCK2	ENSAPLP00000029512	ENSAPLP00000029796	Diaphanous related formin 2.	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.456
ENSAPLP00000020757	ARHGEF18	ENSAPLP00000020757	ENSAPLP00000015636	Uncharacterized protein.	Uncharacterized protein.	0.426
ENSAPLP00000020757	ENSAPLP00000024521	ENSAPLP00000020757	ENSAPLP00000024521	Uncharacterized protein.	EH domain-containing protein.	0.925
ENSAPLP00000020757	RHOA	ENSAPLP00000020757	ENSAPLP00000014536	Uncharacterized protein.	Ras homolog family member A.	0.965