PLEK2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Experiments

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[Homology]

Score

PLEK2

Pleckstrin 2. (370 aa)

Predicted Functional Partners:

PTEN

0.669

ENSAPLP00000030173

0.639

CDC42

0.621

RABIF

0.599

ENSAPLP00000022737

0.595

ENSAPLP00000023164

0.595

PLEKHN1

0.564

LYN

0.561

MCF2

0.557

OSBP

0.555

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSAPLP00000030173	ENSAPLP00000021122	ENSAPLP00000030173	Cell division cycle 42.	Uncharacterized protein.	0.839
CDC42	LYN	ENSAPLP00000021122	ENSAPLP00000005775	Cell division cycle 42.	Tyrosine-protein kinase.	0.513
CDC42	MCF2	ENSAPLP00000021122	ENSAPLP00000027948	Cell division cycle 42.	MCF.2 cell line derived transforming sequence.	0.841
CDC42	PLEK2	ENSAPLP00000021122	ENSAPLP00000014637	Cell division cycle 42.	Pleckstrin 2.	0.621
CDC42	PTEN	ENSAPLP00000021122	ENSAPLP00000015564	Cell division cycle 42.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.591
CDC42	RABIF	ENSAPLP00000021122	ENSAPLP00000018827	Cell division cycle 42.	RAB interacting factor.	0.779
ENSAPLP00000022737	LYN	ENSAPLP00000022737	ENSAPLP00000005775	Uncharacterized protein.	Tyrosine-protein kinase.	0.528
ENSAPLP00000022737	PLEK2	ENSAPLP00000022737	ENSAPLP00000014637	Uncharacterized protein.	Pleckstrin 2.	0.595
ENSAPLP00000023164	LYN	ENSAPLP00000023164	ENSAPLP00000005775	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.528
ENSAPLP00000023164	PLEK2	ENSAPLP00000023164	ENSAPLP00000014637	Protein kinase domain-containing protein.	Pleckstrin 2.	0.595
ENSAPLP00000030173	CDC42	ENSAPLP00000030173	ENSAPLP00000021122	Uncharacterized protein.	Cell division cycle 42.	0.839
ENSAPLP00000030173	LYN	ENSAPLP00000030173	ENSAPLP00000005775	Uncharacterized protein.	Tyrosine-protein kinase.	0.487
ENSAPLP00000030173	PLEK2	ENSAPLP00000030173	ENSAPLP00000014637	Uncharacterized protein.	Pleckstrin 2.	0.639
ENSAPLP00000030173	PTEN	ENSAPLP00000030173	ENSAPLP00000015564	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.745
ENSAPLP00000030173	RABIF	ENSAPLP00000030173	ENSAPLP00000018827	Uncharacterized protein.	RAB interacting factor.	0.611
LYN	CDC42	ENSAPLP00000005775	ENSAPLP00000021122	Tyrosine-protein kinase.	Cell division cycle 42.	0.513
LYN	ENSAPLP00000022737	ENSAPLP00000005775	ENSAPLP00000022737	Tyrosine-protein kinase.	Uncharacterized protein.	0.528
LYN	ENSAPLP00000023164	ENSAPLP00000005775	ENSAPLP00000023164	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.528
LYN	ENSAPLP00000030173	ENSAPLP00000005775	ENSAPLP00000030173	Tyrosine-protein kinase.	Uncharacterized protein.	0.487
LYN	PLEK2	ENSAPLP00000005775	ENSAPLP00000014637	Tyrosine-protein kinase.	Pleckstrin 2.	0.561