STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSDMEGasdermin E. (499 aa)    
Predicted Functional Partners:
CASP3
Caspase 3; Belongs to the peptidase C14A family.
     
 0.789
U3J1K3_ANAPP
Uncharacterized protein; Belongs to the peptidase C14A family.
     
 0.731
NEK7
NIMA related kinase 7; Belongs to the protein kinase superfamily.
      
 0.715
HMGB1
High mobility group box 1.
     
 0.677
U3IA97_ANAPP
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
     
 0.654
U3ITT3_ANAPP
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
     
 0.615
ENSAPLP00000030826
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
     
 0.615
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
      
 0.610
OSBPL6
Oxysterol-binding protein; Belongs to the OSBP family.
 
    
 0.610
U3HZQ3_ANAPP
Uncharacterized protein; Belongs to the peptidase C14A family.
     
 0.577
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.