STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP10Caspase 10; Belongs to the peptidase C14A family. (538 aa)    
Predicted Functional Partners:
FADD
Uncharacterized protein.
   
 0.997
TRADD
TNFRSF1A associated via death domain.
    
 0.992
CFLAR
CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.
   
0.983
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.966
U3J6D9_ANAPP
Uncharacterized protein; Belongs to the peptidase C14A family.
  
  
0.914
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.912
CASP8
Caspase 8; Belongs to the peptidase C14A family.
  
  
0.889
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.881
FAS
Uncharacterized protein.
   
 0.814
U3IDI2_ANAPP
Uncharacterized protein.
    
 0.733
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.