STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT7Sirtuin 7. (408 aa)    
Predicted Functional Partners:
PCYT2
Phosphate cytidylyltransferase 2, ethanolamine.
 
    
 0.925
SIRT1
Sirtuin 1.
  
 
0.728
RRN3
RRN3 homolog, RNA polymerase I transcription factor.
   
  
 0.613
ENSAPLP00000028979
Helicase C-terminal domain-containing protein.
      
 0.611
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
  
 
0.604
SIRT2
Sirtuin 2.
  
   
 0.576
U3I2H1_ANAPP
Uncharacterized protein.
  
 
 0.575
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.575
ENSAPLP00000028245
Uncharacterized protein.
   
 0.567
MAFG
MAF bZIP transcription factor G.
 
    
 0.552
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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