STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XPAXPA, DNA damage recognition and repair factor. (491 aa)    
Predicted Functional Partners:
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
    
 0.985
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
    
 0.983
FANCM
FA complementation group M.
    
 0.972
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
    
 0.965
GTF2H5
General transcription factor IIH subunit 5.
    
 0.964
DDB1
Damage specific DNA binding protein 1.
    
 0.960
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
    
 0.959
GTF2H1
General transcription factor IIH subunit 1.
    
 0.948
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.946
U3IBC3_ANAPP
Uncharacterized protein.
    
 0.934
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.