STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD40TNFR-Cys domain-containing protein. (214 aa)    
Predicted Functional Partners:
CD40LG
CD40 ligand; Belongs to the tumor necrosis factor family.
   
 0.999
CD86
CD86 molecule.
   
  
 0.965
CD4
Ig-like domain-containing protein.
      
 0.938
IL4
Uncharacterized protein.
   
  
 0.924
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
   
 0.894
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.861
IL6
Uncharacterized protein.
   
  
 0.823
IL10
Interleukin 10.
      
 0.815
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
      
 0.804
CD83
CD83 molecule.
   
  
 0.789
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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