STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPLP00000016603UBR-type domain-containing protein. (404 aa)    
Predicted Functional Partners:
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
      
 0.610
GINS2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
      
 0.586
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.586
TMEFF1
Uncharacterized protein.
      
 0.586
NASP
Nuclear autoantigenic sperm protein.
   
 
 0.576
DSCC1
DNA replication and sister chromatid cohesion 1.
      
 0.548
CASP8AP2
Caspase 8 associated protein 2.
      
 0.524
ATAD2
ATPase family AAA domain containing 2.
   
  
 0.497
TRIP12
Thyroid hormone receptor interactor 12.
      
 0.493
CHAF1B
Chromatin assembly factor 1 subunit B.
      
 0.463
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.