STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1051 aa)    
Predicted Functional Partners:
ARID4B
AT-rich interaction domain 4B.
    
 0.862
ARID4A
AT-rich interaction domain 4A.
    
 0.862
SIRT1
Sirtuin 1.
    
 
 0.703
MEF2D
Myocyte enhancer factor 2D.
   
 
 0.691
SIN3B
SIN3 transcription regulator family member B.
   
 0.652
SIN3A
SIN3 transcription regulator family member A.
   
 0.652
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.625
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.622
LARP4
La ribonucleoprotein domain family member 4.
      
 0.607
ENSAPLP00000025536
Ubiquitin-like domain-containing protein.
    
  0.605
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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