P2RX3 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

P2RX3

Purinergic receptor P2X 3. (332 aa)

Predicted Functional Partners:

P2RX2

0.799

P2RX1

0.705

P2RX4

0.660

P2RX6

0.618

P2RX5

0.594

ENSAPLP00000020861

0.555

ENSAPLP00000022103

0.487

P2RY4

0.434

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000020861	P2RX1	ENSAPLP00000020861	ENSAPLP00000003755	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.598
ENSAPLP00000020861	P2RX2	ENSAPLP00000020861	ENSAPLP00000010757	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.442
ENSAPLP00000020861	P2RX3	ENSAPLP00000020861	ENSAPLP00000017240	Uncharacterized protein.	Purinergic receptor P2X 3.	0.555
ENSAPLP00000020861	P2RX4	ENSAPLP00000020861	ENSAPLP00000019702	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.465
ENSAPLP00000020861	P2RX5	ENSAPLP00000020861	ENSAPLP00000005706	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.454
ENSAPLP00000022103	P2RX3	ENSAPLP00000022103	ENSAPLP00000017240	Brix domain-containing protein.	Purinergic receptor P2X 3.	0.487
ENSAPLP00000022103	P2RX5	ENSAPLP00000022103	ENSAPLP00000005706	Brix domain-containing protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.477
P2RX1	ENSAPLP00000020861	ENSAPLP00000003755	ENSAPLP00000020861	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Uncharacterized protein.	0.598
P2RX1	P2RX2	ENSAPLP00000003755	ENSAPLP00000010757	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.944
P2RX1	P2RX3	ENSAPLP00000003755	ENSAPLP00000017240	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Purinergic receptor P2X 3.	0.705
P2RX1	P2RX4	ENSAPLP00000003755	ENSAPLP00000019702	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.951
P2RX1	P2RX5	ENSAPLP00000003755	ENSAPLP00000005706	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.951
P2RX1	P2RX6	ENSAPLP00000003755	ENSAPLP00000008461	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Purinergic receptor P2X 6.	0.961
P2RX1	P2RY4	ENSAPLP00000003755	ENSAPLP00000023707	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.511
P2RX2	ENSAPLP00000020861	ENSAPLP00000010757	ENSAPLP00000020861	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	Uncharacterized protein.	0.442
P2RX2	P2RX1	ENSAPLP00000010757	ENSAPLP00000003755	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.944
P2RX2	P2RX3	ENSAPLP00000010757	ENSAPLP00000017240	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	Purinergic receptor P2X 3.	0.799
P2RX2	P2RX4	ENSAPLP00000010757	ENSAPLP00000019702	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.945
P2RX2	P2RX5	ENSAPLP00000010757	ENSAPLP00000005706	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.966
P2RX2	P2RX6	ENSAPLP00000010757	ENSAPLP00000008461	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	Purinergic receptor P2X 6.	0.946