STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (551 aa)    
Predicted Functional Partners:
ORAI1
ORAI calcium release-activated calcium modulator 1.
   
  
 0.632
ENSAPLP00000019578
Uncharacterized protein.
   
 
 0.582
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.582
ATM
Non-specific serine/threonine protein kinase.
    
 0.566
MC5R
Melanocortin 5 receptor.
      
 0.547
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.546
MDM4
Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.
    
 0.506
AAR2
AAR2 splicing factor.
      
 0.487
PLK2
Serine/threonine-protein kinase PLK.
    
 
0.468
PLK1
Serine/threonine-protein kinase PLK.
    
 
0.468
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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