NUCKS1 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NUCKS1

Nuclear casein kinase and cyclin dependent kinase substrate 1. (292 aa)

Predicted Functional Partners:

RAB29

0.801

PHIP

0.589

SLC15A4

0.539

U3IBC3_ANAPP

0.530

PHAX

0.509

PM20D1

0.497

NCOA5

0.489

C17orf67

0.482

POC5

0.477

SLC41A1

0.465

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C17orf67	NUCKS1	ENSAPLP00000016592	ENSAPLP00000017998	Chromosome 17 open reading frame 67.	Nuclear casein kinase and cyclin dependent kinase substrate 1.	0.482
C17orf67	POC5	ENSAPLP00000016592	ENSAPLP00000022785	Chromosome 17 open reading frame 67.	Uncharacterized protein.	0.611
NCOA5	NUCKS1	ENSAPLP00000013558	ENSAPLP00000017998	Nuclear receptor coactivator 5.	Nuclear casein kinase and cyclin dependent kinase substrate 1.	0.489
NCOA5	PHIP	ENSAPLP00000013558	ENSAPLP00000003113	Nuclear receptor coactivator 5.	Pleckstrin homology domain interacting protein.	0.667
NUCKS1	C17orf67	ENSAPLP00000017998	ENSAPLP00000016592	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Chromosome 17 open reading frame 67.	0.482
NUCKS1	NCOA5	ENSAPLP00000017998	ENSAPLP00000013558	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Nuclear receptor coactivator 5.	0.489
NUCKS1	PHAX	ENSAPLP00000017998	ENSAPLP00000012291	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Phosphorylated adaptor for RNA export.	0.509
NUCKS1	PHIP	ENSAPLP00000017998	ENSAPLP00000003113	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Pleckstrin homology domain interacting protein.	0.589
NUCKS1	PM20D1	ENSAPLP00000017998	ENSAPLP00000012007	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Peptidase M20 domain containing 1.	0.497
NUCKS1	POC5	ENSAPLP00000017998	ENSAPLP00000022785	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Uncharacterized protein.	0.477
NUCKS1	RAB29	ENSAPLP00000017998	ENSAPLP00000004474	Nuclear casein kinase and cyclin dependent kinase substrate 1.	RAB29, member RAS oncogene family.	0.801
NUCKS1	SLC15A4	ENSAPLP00000017998	ENSAPLP00000019270	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Solute carrier family 15 member 4.	0.539
NUCKS1	SLC41A1	ENSAPLP00000017998	ENSAPLP00000018824	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Solute carrier family 41 member 1.	0.465
NUCKS1	U3IBC3_ANAPP	ENSAPLP00000017998	ENSAPLP00000004545	Nuclear casein kinase and cyclin dependent kinase substrate 1.	Uncharacterized protein.	0.530
PHAX	NUCKS1	ENSAPLP00000012291	ENSAPLP00000017998	Phosphorylated adaptor for RNA export.	Nuclear casein kinase and cyclin dependent kinase substrate 1.	0.509
PHIP	NCOA5	ENSAPLP00000003113	ENSAPLP00000013558	Pleckstrin homology domain interacting protein.	Nuclear receptor coactivator 5.	0.667
PHIP	NUCKS1	ENSAPLP00000003113	ENSAPLP00000017998	Pleckstrin homology domain interacting protein.	Nuclear casein kinase and cyclin dependent kinase substrate 1.	0.589
PM20D1	NUCKS1	ENSAPLP00000012007	ENSAPLP00000017998	Peptidase M20 domain containing 1.	Nuclear casein kinase and cyclin dependent kinase substrate 1.	0.497
PM20D1	RAB29	ENSAPLP00000012007	ENSAPLP00000004474	Peptidase M20 domain containing 1.	RAB29, member RAS oncogene family.	0.495
POC5	C17orf67	ENSAPLP00000022785	ENSAPLP00000016592	Uncharacterized protein.	Chromosome 17 open reading frame 67.	0.611