STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBX2Gastrulation brain homeobox 2. (234 aa)    
Predicted Functional Partners:
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 
 0.807
PAX2
Paired box 2.
    
 
 0.778
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 
 0.762
TCF7L2
Transcription factor 7 like 2.
    
 0.649
CDH1
Uncharacterized protein.
   
  
 0.634
ZIC1
Zic family member 1.
    
 0.615
SHH
Sonic hedgehog signaling molecule.
      
 0.611
SIX3
SIX homeobox 3.
      
 0.610
OTX2
Orthodenticle homeobox 2.
      
0.608
FOXG1
Forkhead box G1.
    
 0.601
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.